A Patient Admitted For The Management Of Video
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A Patient Admitted For The Management Of - above told
Create a free QxMD account to take advantage of the features offered by Read like saving your papers and creating collections. No comprehensive clinical guideline for their care exists. To support the development of such a guideline, we sought the views of experts in the field. A total of 70 statements were presented, using an online platform, over three consensus-seeking rounds, to participants with experience in the hospital care of patients with acute vertebral fragility fractures from UK-based specialist societies. Participants rated the level of their agreement with each statement on a 5-point Likert scale. Over the first two rounds, statements not reaching consensus were modified in subsequent rounds, and new statements proposed by participants and agreed by the research team could be added.Either your web browser doesn't support Javascript or it is currently turned off. In the latter case, please turn on Javascript support in your web browser and reload this page. Trials05 Feb22 1 : DOI: De-identified participant data is stored on a secure password protected red-cap data base. Access to the data base will be controlled by the principal investigator. We hypothesize that continuation of RAAS inhibition will be superior to temporary discontinuation with regards to the primary endpoint of a global rank sum score.
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The global rank sum score has been successfully used in previous cardiovascular clinical trials. Of note, the initial protocol to screen and enrol within 48 hours of COVID diagnosis was extended through an amendment, to 96 hours to increase feasibility.
Participants have to be 18 years or older and would have to be on RAAS inhibitors for at least a month to be considered eligible for the study. Additionally, RAAS inhibitors should not have been held for more than 48 hours before randomization.
A list of inclusion and exclusion criteria can be found in the full protocol document. In order to prevent heart failure exacerbation, patients with reduced ejection fraction were excluded from the trial.
Introduction
If the patient is eligible and informed consent has been obtained we will collect data on sex, age, ethnicity, past medical history and list of medications e. All the study participants will be randomized to a strategy of temporarily holding the RAAS inhibitor [intervention] versus continuing the RAAS inhibitor [continued standard of care].
Among participants who are randomized to the intervention arm, alternative guide-line directed anti-hypertensive medication will be provided to the treating physician team detail in study protocol. In the intervention arm RAAS inhibitor will be withheld for a total of 7 days with the possibility of the withdrawn medication being initiated at any point after day 7 or on the day of discharge. The recommendation for re-initiating the withdrawn medication will be made to A Patient Admitted For The Management Of treating physician.
Associated Data
The re-initiation of these therapies are according to standard convention and follow-up as per Canadian guidelines. Additionally, the date of restarting the withdrawn medication or whether the medication was re-prescribed on discharge or not, will be collected. This will be used to conduct a sensitivity analysis.]
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