Learn about cystic fibrosis, a genetic disorder that affects the lungs, pancreas, and other organs, and how to treat and live with this chronic disease.
Microglial and Neurological Disorder
Cystic fibrosis is a progressive, genetic disease that causes persistent lung infections and Adilt the ability to breathe over time. Without the chloride to attract water https://amazonia.fiocruz.br/scdp/blog/culture-and-selfaeesteem/constitutional-conventions-of-the-united-kingdom.php the cell surface, the mucus in various organs becomes thick and sticky. In the lungsthe mucus clogs the airways and traps germs, like bacteria, leading to infectionsinflammationrespiratory failure, and other complications.
For this reason, minimizing contact with germs is a top concern for people with CF. In the pancreasthe buildup of mucus prevents the release of digestive enzymes that help the body absorb food and key nutrientsresulting in malnutrition and poor growth.
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In the liver, the thick mucus can block the bile duct, causing liver disease. In men, CF can affect their ability to have children. Cystic fibrosis is a genetic disease. People with CF have inherited two copies of the defective CF gene -- one copy from each parent. Both parents must have at least one copy of the defective gene. People with only one copy of the defective CF gene are called carriers, but they do not have the disease. Each time two CF carriers have a child, the chances are:. The defective CF gene Asult a slight abnormality called a mutation.
There are more than 1, known mutations of the disease. Most genetic tests only screen for the most common CF mutations.
Therefore, the test results may indicate a person who is a carrier of the CF gene is not a carrier. Diagnosing cystic fibrosis is a multistep process, and should include a newborn screeninga sweat testa genetic or carrier testand a clinical evaluation at a CF Foundation-accredited care center.
The Role of P2X Receptors in Nociception
Although most people are diagnosed with CF by the age of 2, some are diagnosed as adults. A CF specialist can order a sweat test and recommend additional testing Multiplee confirm a CF diagnosis. More than half of the cystic fibrosis population is over Cystic fibrosis is a complex disease and the types and severity of symptoms can differ widely from person to person. Many different factors, such as age of diagnosis, can affect an individual's health and the course of the disease.]
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