Fmri The New Aspects Of Deception Detection - amazonia.fiocruz.br

Fmri The New Aspects Of Deception Detection Video

Fmri The New Aspects Of Deception Detection.

Fmri The New Aspects Of Deception Detection - confirm. was

A lie is an assertion that is believed to be false, typically used with the purpose of deceiving someone. A person who communicates a lie may be termed a liar. Lies may serve a variety of instrumental, interpersonal, or psychological functions for the individuals who use them. Generally, the term "lie" carries a negative connotation, and depending on the context a person who communicates a lie may be subject to social, legal, religious, or criminal sanctions. The potential consequences of lying are manifold; some in particular are worth considering. Typically lies aim to deceive , when deception is successful, the hearer ends up acquiring a false belief or at least something that the speaker believes to be false. When deception is unsuccessful, a lie may be discovered. The discovery of a lie may discredit other statements by the same speaker, staining his reputation.

Objective: Neuroimaging studies on neuropathic pain have discovered abnormalities in brain structure and function. However, the brain pattern changes from herpes zoster HZ to postherpetic neuralgia PHN remain unclear. The present study aimed to compare the brain activity between HZ and PHN patients and explore the potential neural mechanisms underlying cognitive impairment in neuropathic pain patients. The amplitude of low-frequency fluctuation ALFF was analyzed to detect the brain activity of the patients. Correlations between ALFF and clinical pain scales were assessed in two groups of patients.

Differences in brain activity between groups were examined and used in a support vector Decption SVM algorithm for the subjects' classification. Results: Spontaneous brain activity was reduced in both patient groups.

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Compared with HC, patients from both groups had decreased ALFF in the precuneus, posterior cingulate cortex, and middle temporal gyrus. Meanwhile, the neural activities of angular gyrus and middle frontal gyrus were lowered in HZ and PHN patients, respectively. Conclusion: Our study indicated that mean ALFF Deteection in these pain-related regions can be used as a functional MRI-based biomarker for the classification of subjects with different pain conditions.

Altered brain activity might contribute to PHN-induced pain. Herpes zoster HZ is one of the leading causes of severe pain link China, with a prevalence estimated to be 7. Moreover, Neuropathic pain is well-understood to have a negative impact on the quality of life and a significant impact on cognitive function, including attention, memory, and executive functions 2.

Previous studies have shown that peripheral neuropathic pain arises from injury of the peripheral and the central nervous systems 3 — 5. HZ is caused by the reactivation Deceptiom varicella zoster virus and produces typical neuropathic pain. HZ is characterized by a painful erythematous rash in the affected dermatome 6. PHN is a prototypical human chronic neuropathic condition exhibiting multiple signs of peripheral and central neuropathy 7.

The clinical manifestations include burning, tingling, hyperesthesia, and allodynia in the affected here.

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Although previous studies have shown that Fmri The New Aspects Of Deception Detection pain can change brain plasticity 8the basis of the brain structural and functional changes in patients with neuropathic pain is not clear. Previous neuroimaging studies have reported that patients with PHN showed anatomical changes in the bilateral insula, superior temporal gyrus, left middle frontal gyrus, and right thalamus 9.

Abnormal functional activation and intrinsic activity were detected in regions including the thalamus, insula, somatosensory, putamen, amygdala, brainstem, prefrontal lobe, and cerebellum 10 — Quantitative cerebral blood flow CBF mapping in PHN patients showed significantly increased CBF values in the striatum, thalamus, insula, amygdala, and primary somatosensory cortex and decreased CBF values in the frontal cortex 5. The functional connectivity between these pain-related regions and the notable connections between the putamen and other brain click here were altered in PHN patients A negative correlation was found between PHN patients' pain scores and intrinsic activity in the prefrontal cortex These works indicated that the functional connectivity between the prefrontal regions and other cortical regions was modulated by pain intensity.

Additionally, a graph—theoretic approach was used to calculate the small-world network alterations in PHN patients. The PHN patients exhibited decreased local efficiency and significant changes of regional nodal efficiency in the postcentral gyrus, inferior parietal gyrus, thalamus, para-hippocampus, and putamen All the above studies indicate that chronic pain in PHN patients would modulate the activity and the connectivity of these pain-related regions. The vast majority of these Fmri The New Aspects Of Deception Detection neuroimaging studies were restricted to PHN patients. Only a few studies have used neuroimaging methods to explore the differences in brain activity between HZ and PHN 11 A previous study identified that HZ patients showed significant functional changes in the cerebellum, occipital lobe, temporal lobe, parietal lobe, and limbic lobe in contrast to PHN patients One recent longitudinal neuroimaging study also assessed the brain imaging changes from HZ to PHN and found that the activity of the cerebellum and frontal lobes increased and the activity of the occipital lobe and limbic lobe decreased significantly during this transition Although previous literature confirmed that the brain function of patients with HZ and PHN was changed compared with the HC, the differences in brain activity between HZ and PHN were inconsistent across these studies, and the neural mechanism is still unclear.

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Based on previous literature, we hypothesized that patients with HZ and PHN exhibit significant changes source spontaneous brain activity, which can be used to classify them from healthy controls. Thus, the present study aimed to explore the effects of HZ and PHN on brain activity and detect the neural mechanism underlying cognitive impairment in neuropathic pain patients.

Resting-state functional MRI data were collected from all participants, and the amplitude of low-frequency fluctuation ALFF was calculated. The ALFF is the most common and widely used method for characterizing the dynamic properties of the neuronal processing unit The correlations between clinical pain scales and spontaneous brain activity were also assessed. Additionally, to evaluate the stability of the group comparison results, imaging features with significant differences between groups were applied for classification using support vector machine SVM.]