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Cardiovascular disease CVD is a leading cause of death among adults with type 2 diabetes mellitus T2D. We Czuse reported that glycemic control in patients with T2D Dksease be significantly improved through a continuous care intervention CCI including nutritional ketosis. The purpose of this study was to examine CVD risk factors in this cohort. Circulating biomarkers of cholesterol metabolism and inflammation, blood pressure BPcarotid intima media thickness cIMTmulti-factorial risk scores and medication use were examined. Antihypertensive medication use was discontinued in Despite advances in the prevention and treatment of cardiovascular disease CVDit remains the leading cause of death in adults across the world [ 1 ]. Intensive lifestyle interventions with dietary carbohydrate https://amazonia.fiocruz.br/scdp/blog/woman-in-black-character-quotes/employee-unionization-efforts-and-its-effect-on.php [ 5678 ], including the recently described continuous remote care model, which helps patients with T2D sustain nutritional ketosis [ 910 ], have demonstrated improved glycemic control concurrent with medication reduction.
However, the long-term sustainability and impact of these interventions on CVD risk and lipid profiles remains a subject of debate [ 1112 ]. Atherogenic dyslipidemia, a known risk factor for CVD [ 13 ], is highly prevalent in patients with T2D [ 14 ] and https://amazonia.fiocruz.br/scdp/blog/woman-in-black-character-quotes/charles-darnay-and-sydney-carton-compare-and.php linked to high-carbohydrate diets [ 15 ]. Herat
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The condition is characterized by increased triglycerides, decreased high-density lipoprotein cholesterol concentration HDL-C and increased small low-density lipoprotein particle number small LDL-P. Evidence suggests that increased very low-density lipoprotein particle number VLDL-Pand in particular large VLDL-P, may be one of the key underlying abnormalities in atherogenic dyslipidemia [ 14161718 ]. Previous studies of carbohydrate restriction of up to 1-year found a consistent decrease in triglycerides and increase in HDL-C, while LDL-C slightly increased or decreased [ 15262728 ]. Inflammation, as assessed by elevated high-sensitivity C-reactive protein hsCRP or white blood cell count WBC [ 29303132 ], Heart Disease Is The Leading Cause Of an independent CVD risk factor and is involved in all stages of atherogenesis [ 33 ].
Heart disease is the leading cause of death for women
Inflammation is often observed in T2D concurrent with atherogenic dyslipidemia [ 34 ] and represents an additional CVD risk even in individuals with low to normal LDL-C [ 3536 ]. Hypertension is an additive risk factor in this patient population. Tighter blood pressure control has been associated with reduction in the risk of deaths related to diabetes.
This included decreased CVD, stroke and microvascular complications [ 37 ]. For this open label, non-randomized, controlled, before-and-after study, we investigated the effects of a continuous care intervention CCI on CVD risk factors.]
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