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Organ Shortage Video

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Language: English French. Reducing wait list mortality among patients awaiting liver transplantation remains a substantial challenge because of organ shortage. In efforts to expand the donor pool there has Organ Shortage a trend toward increased use of donation after circulatory death DCD liver grafts. However, these marginal grafts are prone to higher complication rates, particularly biliary complications.

In addition, many procured DCD livers are then deemed unsuitable for transplant.

Despite these limitations, DCD grafts represent an important resource to Organ Shortage the current organ shortage, and as such there are research efforts directed toward improving the use of and outcomes for transplantation of these grafts. We review the current progress in DCD liver transplantation.

Organ Shortage transplant remains the definitive treatment for end-stage liver disease. InCanadians either died while on the Otgan list or became too sick to undergo the operation. Donation after Organ Shortage death differs from the more common donation after neurological death DND. Before procurement, DCD livers are exposed to a period of warm ischemia time WIT after cardiopulmonary arrest in which the organ is no longer perfused; in DND livers, perfusion persists right up until the moment of procurement in the operating room.

As a result, higher complication rates persist.

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Organ Shortage Of these, we reviewed those that matched best. Relevant articles from the references listed in select articles were also reviewed. When possible, we discussed the highest level of evidence in randomized controlled trials; however, this level of Organ Shortage was limited and, therefore, observational data were also reviewed. The same improvement has not been observed regarding ischemic cholangiopathy ICdefined as the occurrence of multiple intrahepatic strictures in the absence of hepatic artery thrombosis or stenosis. Ischemic cholangiopathy leads to higher rates of graft failure, longer hospital admissions, increased biliary procedures, retransplantation and overall increased health care costs.

Older donor age has been identified consistently as a risk factor for complications in DCD liver transplantation. Rising obesity rates have resulted in increasing numbers of donors with steatosis.]