Causes And Treatment Of Lymphatic Filariasis Video
Lymphatic Filariasis Elimination Program: Alleviating Suffering, Ending Shame Causes And Treatment Of Lymphatic Filariasis.
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Background: Improved drug regimens are needed to accelerate elimination of lymphatic filariasis in Africa. This study determined whether a single co-administered dose of ivermectin plus diethylcarbamazine plus albendazole [IDA] is noninferior to standard 3 annual doses of ivermectin plus albendazole IA used in many LF-endemic areas of Africa.
The primary endpoint was the proportion of participants who were microfilaria Mf negative at 36 months. Secondary endpoints were Mf clearance at 6, 12, and Cuses months; inactivation of adult worm nests; and safety. IDA was superior to IA for inactivating adult worms at all time points.
Both treatments were well tolerated, and there were Lymphaitc serious adverse events. Reinfection may have contributed to the lack of sustained clearance of Mf with IDA. Clinical trials registration: NCT Keywords: albendazole; diethylcarbamazine; efficacy; ivermectin; lymphatic filariasis. Abstract Background: Improved drug regimens are needed to accelerate elimination of lymphatic filariasis in Africa.
Associated data ClinicalTrials.]
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