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Rheumatoid Arthritis and Its Effects on Todays Video

Rheumatoid arthritis - causes, symptoms, diagnosis, treatment, pathology Rheumatoid Arthritis and Its Effects on Todays

Rheumatoid arthritis RA is a long-term autoimmune disorder that primarily Rheumatlid joints. While the cause of rheumatoid arthritis is not clear, it is believed to involve a combination of genetic and environmental factors. The goals of treatment are to reduce pain, decrease inflammation, and improve a person's overall functioning.

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RA affects about Arthritis of joints involves inflammation of the synovial membrane. Joints become swollen, tender and warm, and stiffness limits their movement. With time, multiple joints are affected polyarthritis. Most commonly involved Todayz the small joints of the handsfeet and cervical spinebut larger joints like the shoulder and knee can also be involved.

Rheumatoid Arthritis and Its Effects on Todays

RA typically manifests with signs of inflammation, with the affected joints being swollen, warm, painful and stiff, particularly early in the morning on waking or following prolonged inactivity. Increased stiffness early in the morning is often a Afthritis feature of the disease and typically lasts for more than an hour. Gentle movements may relieve symptoms in early stages of the disease. These signs help distinguish rheumatoid from non-inflammatory problems of the joints, such as osteoarthritis.

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In arthritis of non-inflammatory causes, signs of inflammation and early morning stiffness are less prominent. As the pathology progresses the inflammatory activity leads to tendon tethering and erosion and destruction of the joint surface, which impairs range of movement and leads to deformity. The fingers may suffer from almost any deformity depending on which joints are most involved. Specific deformitieswhich also occur in osteoarthritisinclude ulnar deviationboutonniere deformity also "buttonhole deformity", flexion of proximal interphalangeal joint and extension of distal interphalangeal joint Efffects the handswan neck deformity hyperextension at proximal interphalangeal joint and flexion at distal interphalangeal joint and "Z-thumb.

In the worst case, joints are known as arthritis mutilans due to the mutilating nature of the deformities. The initial pathologic process in nodule formation is unknown but may be essentially the same as the synovitis, since similar structural features occur in both. The nodule has a central area of fibrinoid necrosis that may be fissured and which corresponds to the fibrin -rich Artnritis material found in and around Arthrihis affected synovial space. Surrounding Rheumatoid Arthritis and Its Effects on Todays necrosis is a layer of palisading macrophages and fibroblastscorresponding to the intimal layer in synovium and a cuff of connective tissue containing clusters of lymphocytes and plasma cells Rheumatoid Arthritis and Its Effects on Todays, corresponding to the subintimal zone in synovitis.

The typical rheumatoid nodule may be a few millimetres to a few centimetres in diameter and is usually found over bony prominences, such as the elbowthe heelthe knucklesor other areas that sustain repeated mechanical stress.]

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