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In your explanation, include why their explanations make physiological sense or why they do not. Cystic Fibrosis is an autosomal recessive disease that affects chromosome 7 on the DNA helix. The parents of the child with cystic fibrosis are both carriers of the disorder and likely have no symptoms and have no idea they are carriers. The disease is caused by a mutation in cystic fibrosis transmembrane regulator CFTR. The CFTR regulates the flow of salt and fluids in and out of the cell. The CFTR protein provides instructions for the channel than transports negatively charged particles called chloride ions in and out of the cell and across the tissues. The lack of this channel causes the build-up of thick and sticky mucus because chloride helps with the movement of water across the tissues that assist with thinning the mucus.

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Cystic fibrosis CF is a genetic disorder that affects mostly the lungs , but also the pancreas , liver , kidneys , and intestine. CF is inherited in an autosomal recessive manner. There is no known cure for cystic fibrosis. CF is most common among people of Northern European ancestry and affects about one out of every 3, newborns. The main signs and symptoms of cystic fibrosis are salty-tasting skin , [11] poor growth and poor weight gain despite normal food intake, [12] accumulation of thick, sticky mucus, [13] frequent chest infections, and coughing or shortness of breath. Cystic Fibrosis An Recessive Disease Cystic Fibrosis An Recessive Disease

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Cystic Fibrosis An Recessive Disease

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Cystic Fibrosis An Recessive Disease

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Cystic Fibrosis An Recessive Disease

Literature Guides. In humans, Cystic Fibrosis is caused by a recessive allele on chromosomes 7.

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A person must inherit two of these alleles to have the disease. What are the chances of a child having the disease if both of the parents are heterozygous? Want to see the step-by-step answer?]

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