The Efficacy Of Methotrexate Mtx Versus Placebo
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Sign In with a Versus Arthritis account. I have had PsA for the past year ish.
It's been bad - it started suddenly with no previous psoriasis hTe it was in most joints and the pain was extreme. My toes became bent at odd angles after just a few weeks. Link am 32 and unable to work because my health is so out of control. Prednisolone sorted it initially while I waited for proper treatment. Since then the joints have been gradually improving though it's still pretty bad. I tried sulphasalazine - that didn't do much. Then started Mtx tablets 20mg on top of the sulph, which made me sick as hell and didn't work.
Unmet Needs in Rheumatoid Arthritis
Then I went onto the mtx injections, which worked initially for the joints but were beginning Methotrexae lose effectiveness after a couple of months, but at which point I was just so sick that I was actually happy when the clinic phoned to tell me to stop taking everything as my liver enzymes were very high. I am so shocked I am being told to carry on with mtx after being so unwell for months and clearly it is affecting my liver. Has anyone else been in a similar situation and what did you do? I am finding it hard to trust my rheum practice as they seem quite pushy about mtx generally The Efficacy Of Methotrexate Mtx Versus Placebo I'm just not convinced this is all ok. Hi GSZ. I see that you have PsA and have been unable to work as a result.
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This can happen and has happened to lots of us at times. It is reassuring that tests picked it up before you felt ill. This isn't the same at all, but my youngest was treated for leukaemia at 16 and one of the chemos Asparaginase sp gave her acute liver injury. She was extremely ill; yellow and in hospital for a lengthy period of recovery. She had to have the same drug again. Effciacy
I was terrified, but this time she was fine. I wonder whether they are loathe to look into next steps while we are in the middle of this pandemic? Just a thought.
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I can understand your worry about restarting the MTX - even though it with sulf is very often a good combo for PsA. You said you took one folic acid a week? It might be possible to get that increased to minimise some of the side effects. Hi, Welcome! Febin Living with arthritis. Hi all, I have had PsA for the past year ish. Feb Hi GSZ Nice to meet you.]
Now all is clear, many thanks for the help in this question. How to me you to thank?
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