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Individuals with high carotenoid brain concentrations perform significantly better when compared to individuals with low carotenoid brain concentrations of the same age in terms of cognitive function. In other words, they have better memory, attention and processing skills. Cognitively healthy individuals that are supplemented with a specific formulation of carotenoids found in Memory Health demonstrated improvements in cognitive brain function when compared to individuals that received a placebo a supplement containing no active carotenoids or omega-3 fatty acids. This important work is now being repeated in a larger trial and results are expected in the summer of We are fortunate to live in a time where people live much longer than before. However, we can only celebrate aging if function and quality of life is maintained and supported. Aging Is Often Associated With Gradual Cognitive.

Aging Is Often Associated With Gradual Cognitive Video

Cognitive Aging Summit III - Session 2 General Discussion

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Purpose: Loss of grip strength and cognitive impairment are prevalent in the elderly, and they may share the pathogenesis in common. Several original studies have investigated the association between them, but the results remained controversial. In this systematic review and meta-analysis, we aimed to quantitatively determine the relationship between baseline grip strength and the risk of cognitive impairment and provide evidence for clinical work. Heterogeneity between the studies was examined using I 2 and p- value. Sensitivity analyses and subgroup analyses were also performed, and publication bias was assessed by Begg's and Egger's tests.

Results: Fifteen studies were included in this systematic review. Conclusions: Lower grip strength is associated with Associatdd risk of onset of cognitive decline and dementia despite of subtype of dementia. We should be alert for the individuals with poor grip strength and identify cognitive dysfunction early.

Physical performance gradually declines with aging, and loss of grip strength is also a well-recognized manifestation of age-related motor decline and of geriatric syndromes such as sarcopenia and frailty Buchman et al. Measure of grip strength is noninvasive and widely available Ferlay et al. Being sensitive to age-related changes and changes in biological function, grip strength is not only an indicator of muscle strength but also of biological vitality MacDonald et al.

Furthermore, cognitive decline and dementia are common outcomes of aging that significantly affect the quality of life of the elderly people.

Cognitive decline is frequently regarded as a prodrome to dementia, but exists on a continuum with normal aging Heward et al. Individuals with cognitive decline are nevertheless at high risk of developing cognitive impairment and dementia.

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It is reported that sarcopenia leads to physical inactivity, and physical decline has been consistently associated with future cognitive decline Cabett Cipolli et al. Inflammatory and hormonal pathway and brain atrophy might be the explanation for the association between sarcopenia and cognitive impairment Iannuzzi-Sucich et al.

Besides, frailty is common in the elderly. Frailty was defined as a clinical Cognitivs in which three or more of the following criteria were present: unintentional weight loss 10 lbs in past yearself-reported exhaustion, weakness low grip strengthslow walking speed, and low physical activity Fried et al. Frailty and AD may share underlying pathogeneses, and the rates of change of frailty and cognition over time are strongly associated with the same brain pathologies, such as the presence of macroinfarcts, Alzheimer's disease pathology, and nigral neuronal loss Buchman et al. Besides, sarcopenia, frailty and cognitive impairment are all correlated to aging, oxidative stress and inflammation and so on. A recent meta-analysis Peng et al.

Systematic Review ARTICLE

Another systematic review Zammit et al. Older individuals with low handgrip strength click here show symptoms that can interfere with cognitive and physical performance, such as declines in mobility and balance and impairment in executive function and memory Firth et al. Grip strength, as an important component of sarcopenia and frailty, was also reported to be associated with cognitive aging Zammit et al. It's of great benefit that regarding grip strength as an observational indicator, and discerning cognitive impairment at the early stages. Several studies have reported that poorer grip strength was associated with cognitive decline and onset of dementia Heward et al.]