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The aim of the authors was to summarize the effectiveness of structured interventions upon PA outcomes, in addition to proportions of individuals adopting and maintaining PA, and adherence and retention rates. Methods : Systematic review with narrative synthesis and exploratory meta-analyses. Twelve studies were included. Results : Effectiveness on PA levels during adoption pre- to first time point showed a trivial standardized effect 0. Retention at follow-up did not differ between structured PA or controls Furthermore, though retention is often reported and is similar between interventions and controls, adoption, maintenance, and adherence rates were rarely reported rendering difficulty in interpreting results of effectiveness of structured PA interventions. Mann is with the 4global, London, United Kingdom. Prevalence of insufficient physical activity among adults: Data by WHO region. Sport England.

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The Analysis and Evaluation of the Effectiveness

A randomized controlled trial or randomized oof trial ; [2] RCT is a type of scientific often medical experiment that aims to reduce certain sources of bias when testing the effectiveness of new treatments; this is accomplished by randomly allocating subjects to two or more groups, treating them differently, and then comparing them with respect to a measured response.

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One group—the experimental group—receives the intervention being assessed, while the other—usually called the control group—receives an alternative treatment, such as a placebo or no intervention. The groups are monitored under conditions of the trial design to determine the effectiveness of the experimental intervention, and efficacy is assessed in comparison to the control.

The trial may be blindedmeaning that information which may influence the participants is withheld until after the experiment is complete. A blind can be imposed on any participant of an experiment, including subjects, researchers, technicians, data analysts, and evaluators.

The Analysis and Evaluation of the Effectiveness

Effective blinding may reduce or eliminate some sources of experimental bias. The randomness in the assignment of subjects to groups reduces selection bias and allocation bias, balancing both known and unknown prognostic factors, in the assignment of treatments. A well-blinded RCT is often considered the gold standard for clinical trials.

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Blinded RCTs are commonly used to test the efficacy of medical interventions and may additionally provide information about adverse effects, such as drug reactions. A randomized controlled trial can provide compelling evidence that the study treatment causes an effect on human health.

The Analysis and Evaluation of the Effectiveness

The terms "RCT" and " randomized trial " are sometimes used synonymously, but the latter term omits mention Efectiveness controls and can therefore describe studies that compare multiple treatment groups with each other in the absence of a control group. The term randomized controlled clinical trial is an alternative term used in clinical research ; [9] however, RCTs are also employed in other research areas, including many of the social sciences.

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The first reported clinical trial was conducted by James Lind in to identify treatment for scurvy. Fisher's experimental research and his writings popularized randomized experiments.

The Analysis and Evaluation of the Effectiveness

The first published RCT in medicine appeared in the paper entitled " Streptomycin treatment of pulmonary tuberculosis ", which described a Medical Research Council investigation. Trial design was further influenced by the large-scale ISIS trials on heart attack treatments that were conducted in the s. By the late Analjsis century, RCTs were recognized as the standard method for "rational therapeutics" in medicine.]

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