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Edgewise Therapeutics Inc. The Boulder company said last week that it will begin recruiting approximately healthy volunteers and adults with Becker muscular dystrophy for Phase I trials in San Antonio. It intends to complete the study by October EDG is a genetic treatment for Becker muscular dystrophy, a type of MD that causes progressive muscle weakness in the legs and pelvis that affects an estimated one in 17, newborn males worldwide. The drug is also thought to have benefits for patients with Duchennes MD that attacks the entire body and limb-girdle MD that attacks the legs and arms. All three of those muscular dystrophy types are thought to be caused by mutations in the gene that creates dystrophin, a key part of the protein complex that helps develop muscle strength. As of late , the U. The Muscular Dystrophy Was First Discovered By

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Duchenne Muscular Dystrophy: Ryan's Story

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About: Duchenne muscular dystrophy DMD is a severe type of muscular dystrophy that primarily affects boys. Females with a single copy of the defective gene may show mild symptoms.

The Muscular Dystrophy Was First Discovered By

Muscle weakness usually begins around the age of four, and worsens quickly. Muscle loss typically occurs first in the thighs and pelvis followed by the arms. This can result in trouble standing up.

The Muscular Dystrophy Was First Discovered By

Affected muscles may look larger due to increased fat content. Scoliosis is also common.

The Muscular Dystrophy Was First Discovered By

Some may have intellectual disability. It is caused by a mutation in the gene for the protein dystrophin. Dystrophin is important to maintain the muscle fiber's cell membrane.

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Although there is no known cure, physical therapy, braces, and corrective surgery may help with some symptoms. Source : DST. Latest Current Affairs See All. Vajiram IAS.]

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