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Congratulate, simply: Gender Differences For Health And Quality Of

The liver performs hundreds of functions vital to our healthincluding processing food, medicine, alcohol, and other toxins. Research shows that clear differences in liver health and disease exist between women and men.

The study of sex and gender differences in the prevention, presentation, diagnosis, and treatment of diseases is critical to improving health outcomes for all, and liver diseases are no exception. However, the biological pathways behind many of these differences are still largely unknown and need to be studied. When people think of liver health, many only consider diseases caused by consumption of alcohol. But some liver conditions are not caused by alcohol, such as autoimmune liver disorders though alcohol consumption may exacerbate nAd liver diseases. Autoimmune Https://amazonia.fiocruz.br/scdp/blog/woman-in-black-character-quotes/summary-of-iris-marion-youngs-five-faces.php generally are much more common in women than men, including ones that affect the liver. Liver tumor presentation also differs between women and men, with b enign tumors more common in women and malignant tumors more common in men.

For instance, a rare benign tumor called hepatocellular adenoma occurs mostly Gender Differences For Health And Quality Of reproductive-age women and is associated with use of oral contraceptives. One study showed significant reduction in tumor growth with the cessation of oral contraceptive pillsleading researchers to believe sex hormones play Anx pivotal role in the development of these tumors.

Meanwhile, hepatocellular carcinoma HCCthe most common form of liver cancer, occurs more frequently in men. Research in zebrafish found that androgen accelerates tumor progression in females while estrogen attenuates liver tumors in males. While studies suggest hormones are involved in tumor development, more research is needed to determine the exact mechanisms behind this sexual dimorphism.

For example, women generally have less water in their bodies than men, causing the proportional level of alcohol in the blood to be higher. So while men are more likely to experience alcoholic liver disease due to higher rates of alcohol use disorderwomen with alcoholic liver disease show more rapid progression to fibrosis, a buildup of scar tissue in the organ. Fibrosis can lead to serious long-term Healtj issues, such as cirrhosis, in which severe scarring results in poor liver function.

Background

Women are also drinking more than before, increasing concerns about alcohol-related liver diseases. During the COVID pandemic, a national survey found significant increases in heavy drinking and alcohol-related problems for women. In addition, women are Differencew susceptible to drug-induced liver injury and acute liver failure. Researchers theorize the female preponderance of drug-induced liver injury may be related to sex-based differences in the expression of genes that affect liver metabolic function and pathophysiology. But there are certain biological differences that may put women at a disadvantage from this scoring system.

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For example, men typically have higher muscle mass, resulting in naturally higher levels of creatininea chemical byproduct commonly used to measure renal function. Creatinine levels affect overall MELD score, giving men an advantage. Men are also more susceptible to malignant liver cancers, which bumps their MELD scores up, while women are more susceptible to autoimmune and inflammatory diseases, which have no exception built into the system to receive transplants sooner. There are also fewer smaller-sized livers available for transplant into smaller female patients, as men are more likely to engage in risky behaviors that lead to the donation of organs.

In addition, restrictions on geographic allocation of livers make it even more complicated for women https://amazonia.fiocruz.br/scdp/blog/gregorys-punctuation-checker-tool/katharina-in-taming-of-the-shrew.php access already-scarce liver transplant options.

Systematic review of transplant policy and procedure could help close this gap in female liver health and bring much-needed transplants to a disadvantaged health population. A better understanding of how sex and gender differences affect liver health and disease is vital to achieving individualized health care and informed decision-making for all patients. Continued research is needed on the different ways that sex and gender may influence the FFor, prevention, diagnosis, and treatment of liver diseases in order to bring us another step closer to keeping women healthy. SWHR maintains editorial control and independence over blog content.

What is gender identity?

Autoimmune Liver Disorders When people think of liver health, many only consider diseases caused by consumption of alcohol. Liver Tumors Liver tumor presentation also differs between women and men, with b enign tumors Healty common in women and malignant tumors more common in men. Further Need in Liver Sex Difference Research A better understanding of how sex and gender differences affect liver health and disease is vital to achieving individualized health care and informed decision-making for all patients.]