The Survival Rate Of Systemic Lupus Erythematosus - understand
Study record managers: refer to the Data Element Definitions if submitting registration or results information. Systemic lupus erythematosus SLE is a rare and potentially life-threatening auto-immune systemic disease. There is an urgent need for better comprehension of the physiopathology of the disease and to discover new therapeutic pathways. The hexosamine biosynthesis pathway, or HBP, is an important regulator of immunity and results in a post-transductional modification of proteins called O-GlcNAcylation and involved in inflammation and immunity. There is a very unbalanced sex ratio in favor of women in SLE suggesting a role of the X chromosome in the physiopathology of the disease. Moreover, genes encoding CD40L, CXCR3 and OGT have been shown to be demethylated and overexpressed in T cells of women with systemic systemic lupus erythematosus compared to men with the same pathology. The investigators hypothesize that O-GlcNAcylation is increased in the effector lymphocytes of SLE patients and involved in the pathophysiology of the disease. Among classical disease activity information, blood samples will be collected at study visit to study O-GlcNAcylation levels in immune cells. Fundamental research will be realized on patients' sample. Clinical and biological disease activity, treatment and outcomes will be studied in correlation with O-GlcNAcylation levels.The Survival Rate Of Systemic Lupus Erythematosus - pity, that
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| Personal Choice And Freedom In The Giver | 3 days ago · Systemic Lupus Erythematosus - Pipeline Review, H2 Summary Systemic Lupus Erythematosus - Pipeline Review, H2 , provides an overview of the Systemic Lupus Erythematosus (Immunology) pipeline landscape. Systemic lupus erythematosus (SLE) is an autoimmune disease that causes a chronic infl. 4 days ago · Systemic lupus erythematosus (SLE) is a devastating autoimmune disorder with a wide variety of clinical symptoms predominantly affecting cutaneous, musculoskeletal, cardiovascular, and respiratory systems. SLE-related complications result in more than 10, hospitalizations per year. Oct 14, · The main targets of systemic lupus erythematosus (SLE) management are considered to be as follows: attainment of disease remission or the lowest possible level of disease activity, prevention of disease flares and prevention of organ damage [].Indeed, remission and a low disease activity state (LLDAS) are linked to better outcomes in terms of organ damage preservation [], fewer . |
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| The Core Product Of Ryanair | 4 days ago · Systemic lupus erythematosus (SLE) is a complex autoimmune multisystemic disease of great clinical heterogeneity and significant potential morbidity a. The coexistence of Sjogren’s syndrome with lupus was first described in Since that report, numerous studies have compared and contrasted the two diseases. Many of the clinical and serological (blood-related) features of SS and lupus make the precise diagnosis difficult because there are similarities between the two diseases. Objective: To evaluate the performance in classifying systemic lupus erythematosus by the Systemic Lupus International Collaborating Clinics criteria (SLICC'12), versus the revised American College of Rheumatology criteria from (ACR'97) in adult and juvenile SLE patients. Methods: A systematic literature search was conducted in PubMed and Embase for studies comparing SLICC'12 . |
The Survival Rate Of Systemic Lupus Erythematosus Video
Systemic Lupus Erythematosus (SLE) 8/24/16For unlimited access to articles, videos and more, upgrade your account to PainCast Pro!
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Archives of Rheumatology. Objectives: This study aims to determine the rate, causes, and risk factors of mortality in Turkish systemic lupus erythematosus SLE patients and whether age at diagnosis has an effect on mortality or not. Patients and methods: We retrospectively analyzed the data from patients 10 males, females; mean age Detailed clinical findings, organ involvements, autoantibodies, and complement levels of the patients were recorded. Results: Of the entire group, 19 patients 8.
Mortality incidence rate was 1. Most frequent causes of death were infections, ischemic cardiovascular and cerebrovascular diseases.
Background
Systemmic Beyond the mentioned factors, organ involvements in SLE, autoantibodies or antiphospholipid antibody syndrome were not found here have a relationship with mortality. Cumulative five-year, year, and year survivals of patients were Conclusion: We identified older age at diagnosis as an effective factor on mortality.
SLE patients who are diagnosed at an older age should be more closely and meticulously followed-up than those diagnosed earlier in terms of their mortality risk. You must be logged in to post a comment. Try Pro.
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