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Please enable JavaScript. Coggle requires JavaScript to display documents. Systemic Lupus Erythematosus, - Coggle Diagram. Triggered by the development or activation of CD4 helper T cells that react with a specific autoantigen. Based on various evidence, it is now proposed that a specific antigenic stimulus is the first trigger of autoimmunity. For example, molecular mimicry in which immune response occurs to both an external microbial antigen and an autoantigen because of their homology is considered one of the mechanisms of initiating autoimmunity.

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Systemic Lupus Erythematosus - I - Rheumatology Lectures - Medical Education - V-Learning Systemic Lupus Erythematosus And Its Effects On Systemic Lupus Erythematosus And Its Effects On

The following article is a part of conference coverage from the American College of Rheumatology Convergencebeing held virtually from November 5 to 9, The team at Rheumatology Advisor will be reporting on the latest news and research conducted by leading experts in rheumatology.

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Check back for more from the ACR Convergence Rapid and sustained improvements in skin-specific systemic lupus erythematosus SLE were seen in patients with mild to severe baseline cutaneous activity who received anifrolumab, according to study results presented at the Effefts College of Rheumatology ACR Convergenceheld virtually from November 5 to 9, Data were pooled from both the week, randomized, double-blind trials, and skin responses were compared between patients receiving anifrolumab and those receiving placebo.

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Systemic Lupus Erythematosus And Its Effects On

In total, patients with moderate to severe active SLE received mg of intravenous anifrolumab every 4 weeks for 48 weeks, along with their standard-of-care treatment. A total of patients received placebo.

Systemic Lupus Erythematosus And Its Effects On

At baseline, Researchers recorded separation between treatment groups as early as week 8 difference, The study was sponsored by AstraZeneca. Early and sustained reduction in severity of skin disease with anifrolumab treatment in patients with active SLE measured by the cutaneous Effectd erythematous disease area and severity index CLASI : pooled data from 2 phase 3 studies. Abstract Sign in here. Show More. Login Register.

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Systemic Lupus Erythematosus And Its Effects On

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