Criteria for Diagnosing Major Depression Disorder - amazonia.fiocruz.br

Criteria for Diagnosing Major Depression Disorder Video

Eighty participants, ages Diiagnosing to 65, who meet Diagnostic and Statistical Manual of Mental Disorders DSM-5 criteria for major depressive disorder MDD will be stratified by study site and randomized with a 1-to-1 allocation under double-blind conditions to receive a single 25 mg oral dose of psilocybin or a single mg oral dose of niacin. Niacin will serve as an active placebo.

Trial Purpose and Description

The purpose of this study is to evaluate the potential efficacy of Disoder single 25 mg oral dose of psilocybin for MDD compared to the active placebo in otherwise medically-healthy participants, assessed as the difference between groups in changes in depressive symptoms from Baseline to Day 8 post-dose. The overarching purpose of this study is to conduct an initial examination of the safety, efficacy and tolerability of single-dose therapy with the psychedelic medication, psilocybin, in otherwise medically healthy patients with Major Depressive Disorder MDD.

The overall objectives of this study are to examine the potential efficacy of a single, fixed, 25 mg oral dose of psilocybin in reducing depressive and anxious symptoms and improving functional disability and quality of life in 56 medically healthy patients with MDD when compared to active placebo; and to collect safety and tolerability data on single-dose psilocybin treatment in medically healthy patients with MDD. Of note, this study represents the first randomized, double-blind, placebo-controlled study of single-dose psilocybin Depredsion a general-population i. I nclusion Criteria:. For more information about this study, contact:. Or contact the Help us Discover team on:.

Teenagers And Technology

Skip to Main Content. Phase II. Study HIC : Apply to volunteer.

Trial Purpose and Description. Eligibility Criteria.

Major Depressive Disorder : Specific Symptoms Across Adjacent Episodes

Principal Investigator. For more information about this study, contact: Jane Wanyiri jane. Or contact the Help us Discover team on: helpusdiscover yale.]