Coronary Artery Disease Is Caused By Impaired - amazonia.fiocruz.br

Was: Coronary Artery Disease Is Caused By Impaired

Coronary Artery Disease Is Caused By Impaired Video

A correct diagnosis can guide appropriate medical treatment. Led by researchers and clinicians at NYU Grossman School of Medicine, the study examined women with MINOCA, or myocardial infarction with non-obstructive coronary arteries, a condition that accounts for 6 to 15 percent of heart attacks and is 3 times more common among women than men with heart attack.

It determined that coronary optical coherence tomography OCT and a cardiac MRI identified the underlying cause of heart attack in 85 percent of study participants. Our research provides answers for these women and vital information to guide doctors on how best to treat them.

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In the study, women diagnosed with MINOCA based on an angiogram had two additional imaging tests to determine the cause of their oCronary attack. During a coronary angiogram, the standard test to check on the arteries for patients with heart attack, a catheter is threaded up to the coronary arteries through a small incision in the wrist or groin. During the OCT test, an additional imaging catheter placed inside the coronary arteries uses light to take photographic images of the artery wall, and can find plaques and blood clots that an angiogram can miss. The second test, Dissase cardiac MRI, shows which areas of the heart muscle have been injured and whether that injury is related to lower blood flow, inflammation, or another reason. Researchers enrolled women who had a heart Coronary Artery Disease Is Caused By Impaired across 16 international sites. The median age of study participants was 60 years old, and 50 percent were non-Hispanic white women.

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Three quarters of the women with abnormal OCT or cardiac MRI results had evidence of heart damage from reduced blood flow. This reduced blood flow was determined to be due to ruptured plaque or recently ruptured plaque in most cases. About one third of women with cardiac MRI evidence of heart attack did not have a ruptured plaque to explain the reduction in blood flow. The investigators suggest those women without a recently ruptured plaque and with MRI evidence of heart damage most likely had either artery spasm or a blood clot or plaque rupture in the artery that was not seen. This is a major difference in patients with MINOCA from typical patients with heart attack with Bg blocked arteries, since nearly all typical heart attack is caused by plaque with blood clotting.

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Patients with these diagnoses receive different treatment than patients with heart attack in general. For the remaining 16 percent of the women in the study, both the OCT and cardiac MRI scans were normal, and the cause of the heart attack was not found.

In addition to Dr. SmilowitzMD; Kevin P.

HochmanMD.]