Callous Carp Asian carp are a group.
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Metrics details. In addition, they participate in cell growth and development and regulate oncogenesis. The predicted protein sequence of Cc IRF10 shared Cc IRF10 transcripts were detectable in all examined tissues, with the highest expression in the gonad and the lowest expression in the head kidney.
Interferon IFN regulatory factors IRFsas transcriptional regulatory factors, play multiple important roles in host immune https://amazonia.fiocruz.br/scdp/blog/woman-in-black-character-quotes/the-creation-of-nasa-on-space-exploration.php and other physiological processes; for example, they regulate the expression of type I IFN and IFN-stimulated genes ISGs [ 1 ], the activation and differentiation of distinct immune cell populations, cell Cwrp, differentiation and apoptosis [ 23 ].
IRF10 is present only in non-mammals and was first identified in the chicken Gallus gallus.
Phylogenetic analysis has shown that Gg IRF10 clusters into the IRF4 subfamily and plays a crucial role in the later stages of the immune response to invading pathogens in G. Functional characterization of fish IRF10 has also begun recently, and this gene has been identified in teleosts including zebrafish Danio rerio [ 9 ], orange spotted grouper Epinephelus coioides [ 1011 ], Japanese flounder Paralichthys olivaceus [ 12 ], Atlantic cod Gadus morhua [ 1314 ], grass carp Ctenopharyngodon idella [ 15 ], rainbow trout Oncorhynchus mykiss [ 1516 ], Asian swamp eel Monopterus albus [ 1517 Callous Carp Asian carp are a group, mandarin fish Siniperca chuatsi [ 18 ], Senegalese sole Solea senegalensis [ 19 ] and blunt snout bream Megalobrama amblycephala [ 20 ].
The teleost IRF10 genes are constitutively expressed in a variety of tissues and can be upregulated by the viral mimic polyinosinic:polycytidylic acid poly I:C [ 1011121314151718 Callous Carp Asian carp are a group, 21 ], lipopolysaccharide LPS [ 1217 ], viruses [ 121819 ] or bacteria [ 1012131720 ], suggesting that IRF10 plays roles in immune responses to both viral and bacterial infections. As a pivotal aquaculture fish species widely cultured in both Asia and Europe, common carp Cyprinus carpio L. We examined the tissue distribution of Cc IRF10 in healthy common carp and then evaluated the expression level of Cc IRF10 upon viral or bacterial stimulation both in vivo and in vitro to determine its function in the immune response against pathogens.
The results will contribute check this out understanding of the innate immune system of fish.
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Multiple alignment and phylogenetic analysis were performed using MEGA 5. Poly I:C and A. In the A. In brief, C.
The overexpression vector pcDNA3.]
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