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Male pattern hair loss, or androgenetic alopecia, is the most common type of hair loss among males. Hormonal factors appear to play a role, and especially a male sex hormone known as dihydrotestosterone DHT.

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Hair loss affects around half of all men over the age of 50 years, and around 50 million men in the United States U. DHT has also been linked to hair loss in women, but this article will focus on male pattern baldness. DHT has many roles. Apart from hair production, it is linked to benign prostatic hyperplasia, or enlarged prostate, and prostate cancer too.

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Androgens are responsible for the biological characteristics of males, including a deeper voice, body hair, and increased muscle mass. During fetal development, DHT plays a vital role in the development of the penis and prostate gland.

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In men, the enzyme 5-alpha-reductase 5-AR converts testosterone into DHT in the testes and the prostate. Up to 10 percent of testosterone is normally converted into DHT. DHT is more powerful than testosterone.

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It attaches to the same sites as testosterone, but more easily. Once there, it remains bound for longer. Male pattern hair loss is the most common type of hair loss in men. Hair at the temples and on the crown slowly thin and eventually disappear. The exact reason why this happens is unknown, but genetic, hormonal, and environmental factors are all thought to play a role. DHT is believed to be a major factor. Anagen is the growth phase.]

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