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Correspondence Address : Dr. Users Online: Two hundred asthma patients consisting of 81 Fifty-eight different common aeroallergen tests were tested through skin prick test SPT in patients of bronchial asthma. The sensitivity of all common aeroallergens was analyzed by MS Excel The younger adults aged years were the foremost commonly affected group with 84 The sensitization was the most common in the younger age group patients. Next article. Previous article. Asthma Among Pediatric Patients The University Of

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Asthma in children: Guidelines for primary care management

Objective: Children with pre-school asthma suffer disproportionally more often from severe asthma exacerbations with emergency visits and hospital admissions compared to school children. Despite this high disease burden, there are only a few reports looking at this particular severe asthma cohort. Similarly, there is little real-life research on the distribution of asthma phenotypes and personalized treatment at discharge in this age group. Patients and Methods: Retrospective analysis of the electronic charts of all children aged 1—5 years Asthma Among Pediatric Patients The University Of asthma hospitalizations ICD J45 at the Frankfurt University between and Age, gender, duration of hospitalization, asthma phenotype, treatment, and readmission rate were analyzed. Results: Of patients, met the definition of acute severe Ptaients. The phenotypic characterization showed Of these patients, No phenotype tailored treatment was detectable. Thus, current care and treatment strategies should be reevaluated continuously, in order to better control asthma in pre-school Amogn and prevent hospitalization.

In primary care and emergency departments, acute asthma exacerbations are one of the main causes for pediatric emergency visits 12.

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Although the prevalence of asthma among school children is higher than among pre-school children, severe asthma exacerbations with emergency consultations and hospitalizations are much more common in pre-school children 134. In addition, mortality from pre-school asthma is very high 4. Most likely, due to smaller airways and possibly increased bronchial hyperresponsiveness, pre-school children with asthma are more susceptible to severe asthma exacerbations compared to older children 5.

Shortness of breath due to infections can quickly become life-threatening 34.

This explains the relatively high rate of emergency consultations and hospital admissions in pre-school children. Early identification of children with Ashma asthma who are at risk for persistent asthma is an ongoing challenge for pediatricians. Approximately one-third of infants who wheeze in their first 3 years of life suffer from asthma related events such as wheezing and shortness of breath at school age 6. Thus, even mild wheezing episodes early in life may be a significant risk factor for persistent wheezing and asthma later in life 78.

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Early intervention with anti-inflammatory agents is indicated in pre-school asthma to prevent the development of uncontrolled asthma and frequent exacerbations, which lead to high health care utilization 9 — Although studies are limited, data suggest that an asthma-like inflammation presence of eosinophils and allergic sensitization may be present at a very early age in some children with recurrent wheeze It is important to note that Asthma Among Pediatric Patients The University Of half of the pre-school asthma patients do not present with TH2- inflammation, and may show a Https://amazonia.fiocruz.br/scdp/blog/woman-in-black-character-quotes/nazi-youth-analysis.php like neutrophilic airway inflammation as it was described in adults 15 Currently available anti-inflammatory treatments for first line therapy in pre-school asthma include inhaled corticosteroids ICS and the leukotriene receptor antagonist LTRA montelukast.

Biomarkers of TH2- inflammation here eosinophils, total and elevated sIgE sensitization are useful in the prediction of future exacerbations and may identify children who are likely to respond favorably to daily ICS treatment 13 Thus, asthma exacerbations still occur frequently despite the regular use of ICS. Even quintupling the ICS dose did not reduce the rate of severe asthma exacerbations and may be associated with diminished linear growth 21 In addition, in children with persistent asthma, the combination of ICS and additional long acting beta agonists LABA was not associated with a significant reduction of exacerbations requiring systemic steroids 23 Severe asthma exacerbations with hospitalization are a pivotal event that requires careful reevaluation of the previous asthma treatment and a new personalized approach Asthma Among Pediatric Patients The University Of future asthma management 12 Ideally, the current treatment options should be based on the underlying asthma phenotype Therefore, the aim of this retrospective real-life study was to carry out a detailed analysis of hospitalized pre-school children with acute severe asthma exacerbations duration of hospitalization, age, gender, therapy before admission and after discharge, the asthma phenotype and the readmission rate within 12 months.

In addition, hurdles Awthma physicians' decision to base the current asthma management on the underlying phenotype at discharge as well as the readmission rate in regard to the phenotype were investigated. We carried out a retrospective analysis of the electronic medical records Orbis, version Children suffering from congenital heart disease, genetic diseases such as cystic fibrosis or complex syndromes affecting the respiratory system, or other significant lung diseases such as bronchopulmonary dysplasia and immunodeficiencies were excluded.]