Centro de Estudos vai abordar efeitos da ivermectina na biologia de vetor da malária

A palestra desta semana do Centro de Estudos do Instituto Leônidas e Maria Deane (ILMD/ Fiocruz Amazônia) tem como título “Efeitos da ivermectina na biologia de Anopheles aquasalis: implicações no controle e eliminação da malária”. O tema será abordado pelo pesquisador da Fundação de Vigilância em Saúde do Amazonas (FVS-AM), Vanderson Sampaio, na sexta-feira, 7/7, às 9h, no Salão Canoas, na sede do Instituto, à rua Teresina, 476, Adrianópolis, zona centro-sul de Manaus.

O objetivo é apresentar à ​comunidade científica as descobertas mais recentes sobre os efeitos da Ivermectina, em um dos vetores de malária da América Latina, e as implicações no controle de malária na região. A Ivermectina é uma droga conhecida como endectocida, ou seja, possui efeitos em parasitos internos e externos, é indicada para o​ tratamento de oncocercose, escabiose, pediculose, helmintoses etc.

De acordo com Sampaio, “o principal mecanismo de ação da Ivermectina é nos canais de cloro mediados pelo glutamato. A droga se liga nesses lugares, promovendo desequilíbrio eletrolítico e causando paralisia muscular, levando o organismo-alvo à morte”. O pesquisador destaca que trata-se de um medicamento disponível no Sistema Único de Saúde (SUS), que não é exatamente novo, mas que um novo uso foi dado para ele.

ANOPHELES AQUASALIS

O Anopheles aquasalis é um mosquito, hospedeiro e transmissor da malária, encontrado geralmente no litoral, devido a sua preferência por águas com alguma salinidade, preferência esta que deu origem a seu nome.

Sua distribuição é limitada pelo fator salinidade, pois é mais favorável para o desenvolvimento de suas larvas em ambientes com teor elevado de cloreto de sódio, preferindo águas paradas e salobras, como terrenos temporariamente inundados pelas águas do mar.

SOBRE O PALESTRANTE

Vanderson Sampaio é doutor em Medicina Tropical pela Universidade do Estado do Amazonas (UEA) e Fundação de Medicina Tropical Doutor Heitor Vieira Dourado (FMT-HVD), mestre em Genética e Biologia Molecular pela Universidade Federal do Pará (UFPA), especialista em Bioinformática pelo Laboratório Nacional de Computação Científica (LNCC) e graduado em Biologia também pela UFPA.

É biólogo da FVS-AM desde 2006. Atua principalmente nas áreas de Epidemiologia, bioestatística e análise de dados, entomologia, controle vetorial, georreferenciamento, uso de sistemas de informação geográfica e desenvolvimento de softwares e scripts para análise de bancos de dados computacionais.

CENTRO DE ESTUDOS

O Centro de Estudos do ILMD/Fiocruz Amazônia é um núcleo que oportuniza encontros, palestras, seminários e debates sobre diversos temas ligados à pesquisa e ao ensino para a promoção da saúde.

Os eventos ocorrem às sextas-feiras e deles podem participar estudantes de graduação e pós-graduação, pesquisadores, professores e trabalhadores da área da Saúde. A entrada é franca.

ILMD/Fiocruz Amazônia, por Eduardo Gomes

Foto: divulgação

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